(Q27765346)

2

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L Jayaraman

3

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H Yang

4

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J Massagué

5

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N P Pavletich

A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

6

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language of work or name

English

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publication date

4 September 1998

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published in

Cell

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volume

94

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page(s)

585-94

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issue

5

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cites work

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A transcriptional partner for MAD proteins in TGF-beta signalling

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Smad4 and FAST-1 in the assembly of activin-responsive factor

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Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

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Protein import into the nucleus: an integrated view

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Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

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