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Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta
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scholarly article
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PubMed
PubMed ID
10022869
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3 February 2017
title
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta
(English)
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PubMed
PubMed ID
10022869
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3 February 2017
author name string
C. Wong
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1
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PubMed
PubMed ID
10022869
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3 February 2017
E. M. Rougier-Chapman
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2
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PubMed
PubMed ID
10022869
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3 February 2017
J. P. Frederick
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3
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PubMed
PubMed ID
10022869
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3 February 2017
M. B. Datto
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4
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PubMed
PubMed ID
10022869
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3 February 2017
N. T. Liberati
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5
1 reference
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PubMed
PubMed ID
10022869
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3 February 2017
J. M. Li
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6
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PubMed
PubMed ID
10022869
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3 February 2017
X. F. Wang
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7
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PubMed
PubMed ID
10022869
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3 February 2017
language of work or name
English
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publication date
1 March 1999
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PubMed
PubMed ID
10022869
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3 February 2017
published in
Molecular and Cellular Biology
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PubMed
PubMed ID
10022869
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3 February 2017
volume
19
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PubMed
PubMed ID
10022869
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3 February 2017
issue
3
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PubMed
PubMed ID
10022869
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3 February 2017
page(s)
1821–1830
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PubMed
PubMed ID
10022869
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3 February 2017
cites work
Smads bind directly to the Jun family of AP-1 transcription factors
1 reference
stated in
PubMed Central
reference URL
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17 March 2017
Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene
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PubMed Central
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17 March 2017
TGF-beta signal transduction
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PubMed Central
reference URL
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17 March 2017
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling
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PubMed Central
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17 March 2017
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription
1 reference
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PubMed Central
reference URL
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17 March 2017
Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator
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17 March 2017
Human Smad3 and Smad4 are sequence-specific transcription activators
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17 March 2017
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
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PubMed Central
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17 March 2017
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
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17 March 2017
Smad4 and FAST-1 in the assembly of activin-responsive factor
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17 March 2017
Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
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17 March 2017
MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
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17 March 2017
Receptor-associated Mad homologues synergize as effectors of the TGF-beta response
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17 March 2017
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
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17 March 2017
The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
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PubMed Central
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17 March 2017
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
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The transforming growth factor-beta family
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7 April 2017
A transcriptional partner for MAD proteins in TGF-beta signalling
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PubMed Central
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7 April 2017
Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction
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PubMed Central
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29 September 2017
TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
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PubMed Central
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29 September 2017
CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells
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PubMed Central
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29 September 2017
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation
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PubMed Central
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29 September 2017
TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300
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29 September 2017
Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors
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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members
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29 September 2017
Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-beta
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29 September 2017
Transforming growth factor-beta stimulates interleukin-11 transcription via complex activating protein-1-dependent pathways
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29 September 2017
Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein
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29 September 2017
The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function
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29 September 2017
Dual function of the intron of the rat insulin I gene in regulation of gene expression
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29 September 2017
Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.
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PubMed Central
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29 September 2017
An AP-1 binding sequence is essential for regulation of the human alpha2(I) collagen (COL1A2) promoter activity by transforming growth factor-beta.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83975
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29 September 2017
Heterodimer formation of cJun and ATF-2 is responsible for induction of c-jun by the 243 amino acid adenovirus E1A protein
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PubMed Central
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29 September 2017
In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response
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29 September 2017
Interleukin 1 induction of the c-jun promoter.
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29 September 2017
Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta
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29 September 2017
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
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29 September 2017
Regulation of insulin-like growth factor I transcription by cyclic adenosine 3',5'-monophosphate (cAMP) in fetal rat bone cells through an element within exon 1: protein kinase A-dependent control without a consensus AMP response element
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29 September 2017
Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter
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PubMed Central
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29 September 2017
Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation
1 reference
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PubMed Central
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29 September 2017
Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83975
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29 September 2017
Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor
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PubMed Central
reference URL
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29 September 2017
Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83975
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29 September 2017
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer.
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3 June 2018
SMADs: mediators and regulators of TGF-beta signaling
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PubMed Central
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3 June 2018
JNK is involved in signal integration during costimulation of T lymphocytes.
1 reference
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PubMed Central
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3 June 2018
Growth suppression by transforming growth factor beta 1 of human small-cell lung cancer cell lines is associated with expression of the type II receptor
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PubMed Central
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3 June 2018
A regulatory element in the 5'UTR directs cell-specific expression of the mouse alpha 4 gene
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PubMed Central
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3 June 2018
Early gene responses associated with transforming growth factor-beta 1 growth inhibition and autoinduction in MCF-7 breast adenocarcinoma cells
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3 June 2018
TGF-beta regulation of nuclear proto-oncogenes and TGF-beta gene expression in normal human osteoblast-like cells
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3 June 2018
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
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3 June 2018
Regulation of tyrosine hydroxylase gene expression during transdifferentiation of striatal neurons: changes in transcription factors binding the AP-1 site.
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27 November 2018
TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.
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27 November 2018
TGF-beta signaling, Smads, and tumor suppressors.
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27 November 2018
Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines.
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27 November 2018
Binding of promoter-associated AP-1 is not altered during induction and subsequent repression of the c-jun promoter by TPA and UV irradiation.
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PubMed Central
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27 November 2018
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/10022869
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/10022869
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12 December 2020
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Physical and functional interaction of SMADs and p300/CBP
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/10022869
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.19.3.1821
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PMCID
83975
0 references
PubMed ID
10022869
1 reference
stated in
PubMed
PubMed ID
10022869
retrieved
3 February 2017
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