Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28142605)
Watch
English
TGFbeta signaling in growth control, cancer, and heritable disorders
scientific article (publication date: 13 October 2000)
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
TGFbeta signaling in growth control, cancer, and heritable disorders
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author
Joan Massagué Solé
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
author name string
S W Blain
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
R S Lo
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
language of work or name
English
0 references
publication date
1 October 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
103
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
295-309
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
cites work
Analysis of ALK-1 and endoglin in newborns from families with hereditary hemorrhagic telangiectasia type 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta type II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta and breast cancer: Mammary gland development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Persistence of Müllerian derivatives in males
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BMP type II receptor is required for gastrulation and early development of mouse embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of transforming growth factor beta in human disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A murine model of hereditary hemorrhagic telangiectasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Determinants of specificity in TGF-beta signal transduction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta responsiveness in DPC4/SMAD4-null cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Myc target genes involved in cell growth, apoptosis, and metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smads: transcriptional activators of TGF-beta responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc25 cell-cycle phosphatase as a target of c-myc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for smad6 in development and homeostasis of the cardiovascular system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neural crest apoptosis and the establishment of craniofacial pattern: an honorable death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-finger toxin fold for the extracellular ligand-binding domain of the type II activin receptor serine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hereditary hemorrhagic telangiectasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta signalling from cell membrane to nucleus through SMAD proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bone morphogenetic proteins: multifunctional regulators of vertebrate development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microsatellite instability and mutated type II transforming growth factor-beta receptor gene in gliomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the BMP-2-BRIA ectodomain complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Betaglycan presents ligand to the TGF beta signaling receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression analysis of endoglin missense and truncation mutations: insights into protein structure and disease mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How do small GTPase signal transduction pathways regulate cell cycle entry?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional control by the TGF-beta/Smad signaling system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of two Smad4 proteins in Xenopus. Their common and distinct properties.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High specificity of Müllerian-inhibiting substance signaling in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetics of ventral forebrain development and holoprosencephaly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta signaling, Smads, and tumor suppressors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Primary pulmonary hypertension
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hereditary haemorrhagic telangiectasia with extensive liver involvement is not caused by either HHT1 or HHT2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in CDMP1 cause autosomal dominant brachydactyly type C
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta family signal transduction in Drosophila development: from Mad to Smads.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta-mediated apoptosis in the Ramos B-lymphoma cell line is accompanied by caspase activation and Bcl-XL downregulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nodal signalling in vertebrate development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A structural basis for mutational inactivation of the tumour suppressor Smad4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GDF5 coordinates bone and joint formation during digit development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-independent role of MDM2 in TGF-beta1 resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation analysis of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human colon cancer using genomic DNA and intron primers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human chondrodysplasia due to a mutation in a TGF-beta superfamily member
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc downregulation by transforming growth factor beta required for activation of the p15(Ink4b) G(1) arrest pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smads and early developmental signaling by the TGFbeta superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Smad transcriptional corepressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Smad3 and Smad4 are sequence-specific transcription activators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smad3 mutant mice develop metastatic colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900121-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)00121-5
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1066573
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
OpenCitations bibliographic resource ID
1066573
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1066573
PubMed ID
11057902
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1066573
stated in
Europe PubMed Central
PubMed ID
11057902
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11057902%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
ResearchGate publication ID
12268805
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit