(Q47971299)

7 February 2018

title

Identification of two Smad4 proteins in Xenopus. Their common and distinct properties. (English)

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7 February 2018

author name string

Masuyama N

1

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7 February 2018

Hanafusa H

2

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7 February 2018

Kusakabe M

3

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7 February 2018

Shibuya H

4

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7 February 2018

Nishida E

5

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7 February 2018

language of work or name

English

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publication date

1 April 1999

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7 February 2018

Journal of Biological Chemistry

published in

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7 February 2018

volume

274

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7 February 2018

page(s)

12163-12170

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7 February 2018

issue

17

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7 February 2018

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

Mads and Smads in TGF beta signalling

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TGF-beta signal transduction

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Smads and early developmental signaling by the TGFbeta superfamily

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Smad6 inhibits signalling by the TGF-beta superfamily.

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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21 January 2018

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Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.

21 January 2018

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

21 January 2018

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

21 January 2018

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A human Mad protein acting as a BMP-regulated transcriptional activator

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

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Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

21 January 2018

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

21 January 2018

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Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase

21 January 2018

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Smad5 induces ventral fates in Xenopus embryo

21 January 2018

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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

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Characterization of functional domains within Smad4/DPC4

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

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Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

21 January 2018

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

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The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

21 January 2018

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The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

21 January 2018

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The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

21 January 2018

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Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

21 January 2018

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Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

21 January 2018

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Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo

21 January 2018

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A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

21 January 2018

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A structural basis for mutational inactivation of the tumour suppressor Smad4

21 January 2018

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TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

21 January 2018

1 reference

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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus.

21 January 2018

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Vertebrate embryonic induction: mesodermal and neural patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

Mesoderm-inducing factors and mesodermal patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

Ectodermal patterning in vertebrate embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.12163

21 January 2018

Identifiers

DOI

10.1074/JBC.274.17.12163

1 reference

7 February 2018

PubMed ID

10207044

1 reference

7 February 2018