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Mads and Smads in TGF beta signalling
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instance of
scholarly article
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review article
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stated in
Europe PubMed Central
title
Mads and Smads in TGF beta signalling
(English)
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author name string
L Attisano
series ordinal
1
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J L Wrana
series ordinal
2
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language of work or name
English
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publication date
April 1998
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published in
Current Opinion in Cell Biology
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volume
10
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issue
2
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page(s)
188-94
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cites work
MADR1, a MAD-related protein that functions in BMP2 signaling pathways
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7 January 2021
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Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components
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A structural basis for mutational inactivation of the tumour suppressor Smad4
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation
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7 January 2021
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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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Characterization of functional domains within Smad4/DPC4
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Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase
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7 January 2021
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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
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7 January 2021
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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1
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Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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A human Mad protein acting as a BMP-regulated transcriptional activator
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
Smad5 induces ventral fates in Xenopus embryo
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
A transcriptional partner for MAD proteins in TGF-beta signalling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Smad4 and FAST-1 in the assembly of activin-responsive factor
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
XSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mothers Against Decapentaplegic-Related Protein 2 Expression in Avian Granulosa Cells Is Up-Regulated by Transforming Growth Factor during Ovarian Follicular Development
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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inferred from DOI database lookup
Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Smad6 inhibits signalling by the TGF-beta superfamily
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
retrieved
7 January 2021
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inferred from DOI database lookup
Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Daughters against dpp modulates dpp organizing activity in Drosophila wing development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lessons from hereditary colorectal cancer
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
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Tumor suppressor activity of the TGF-beta pathway in human cancers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
MAD about colorectal cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
retrieved
7 January 2021
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inferred from DOI database lookup
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mad-related genes in the human
1 reference
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Somatic alterations of the DPC4 gene in human colorectal cancers in vivo
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0955-0674%2898%2980141-5
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7 January 2021
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Identifiers
DOI
10.1016/S0955-0674(98)80141-5
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PubMed publication ID
9561843
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ResearchGate publication ID
222340419
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