(Q40584931)

21 September 2017

title

Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1. (English)

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21 September 2017

Mei Wan

1

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21 September 2017

Yi Tang

2

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21 September 2017

Ewan M Tytler

3

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21 September 2017

Chongyuan Lu

4

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21 September 2017

Bingwen Jin

5

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21 September 2017

Selwyn M Vickers

6

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21 September 2017

Lei Yang

7

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21 September 2017

Xingming Shi

8

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21 September 2017

Xu Cao

9

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21 September 2017

language of work or name

English

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publication date

26 February 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

15

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21 September 2017

page(s)

14484-14487

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TGF-beta signal transduction

21 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Oncogenic ras represses transforming growth factor-beta /Smad signaling by degrading tumor suppressor Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C400005200

21 January 2018

Identifiers

DOI

10.1074/JBC.C400005200

1 reference

21 September 2017

1 reference