(Q35691527)

9 August 2017

1 reference

title

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture (English)

1 reference

9 August 2017

Robert J Ingham

1

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9 August 2017

Gerald Gish

series ordinal

2

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9 August 2017

Tony Pawson

series ordinal

3

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9 August 2017

language of work or name

English

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publication date

1 March 2004

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9 August 2017

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9 August 2017

23

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9 August 2017

1972-1984

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9 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207436

9 August 2017

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cites work

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Characterization of interactions between Nedd4 and beta and gammaENaC using surface plasmon resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Characterization of the interactions between Nedd4-2, ENaC, and sgk-1 using surface plasmon resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Smads as transcriptional co-modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A novel pro-Arg motif recognized by WW domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Properties and regulation of glutamine transporter SN1 by protein kinases SGK and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

MHC class I ubiquitination by a viral PHD/LAP finger protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Epithelial sodium channel related to proteins involved in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Defining polyubiquitin chain topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Epithelial sodium channel regulated by aldosterone-induced protein sgk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

When ubiquitin meets ubiquitin receptors: a signalling connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Common variant of human NEDD4L activates a cryptic splice site to form a frameshifted transcript

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Annexin XIIIb: a novel epithelial specific annexin is implicated in vesicular traffic to the apical plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The heterotetrameric architecture of the epithelial sodium channel (ENaC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ubiquitin lys63 is involved in ubiquitination of a yeast plasma membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Annexins: from structure to function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

To make antibodies or not: signaling by the B-cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

C2 domain conformational changes in phospholipase C-delta 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Nuclear import/export of hRPF1/Nedd4 regulates the ubiquitin-dependent degradation of its nuclear substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Rhabdoviruses and the cellular ubiquitin-proteasome system: a budding interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

U box proteins as a new family of ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

NPl1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A new ticket for entry into budding vesicles-ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domain-containing ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

PY motifs of Epstein-Barr virus LMP2A regulate protein stability and phosphorylation of LMP2A-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Lysine-independent ubiquitination of Epstein-Barr virus LMP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Smad6 inhibits signalling by the TGF-beta superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Mutations in the PPPY motif of vesicular stomatitis virus matrix protein reduce virus budding by inhibiting a late step in virion release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The ubiquitin-conjugation system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Genetics of Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

RING finger proteins: mediators of ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Solution structure of a Nedd4 WW domain-ENaC peptide complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

UBE3A/E6-AP mutations cause Angelman syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Subunit stoichiometry of the epithelial sodium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Identification of a set of genes with developmentally down-regulated expression in the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Regulation of B cell fates by BCR signaling components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Annexin XIIIb associates with lipid microdomains to function in apical delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Nitrogen regulation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

CDD: a curated Entrez database of conserved domain alignments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

CDD: a database of conserved domain alignments with links to domain three-dimensional structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

TGF-beta signaling by Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

mGrb10 interacts with Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Identification of developmentally expressed proteins that functionally interact with Nedd4 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Drosophila Nedd4, a ubiquitin ligase, is recruited by Commissureless to control cell surface levels of the roundabout receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The C2 domain calcium-binding motif: structural and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Assembly of Cell Regulatory Systems Through Protein Interaction Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Nedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Extending the C2 domain family: C2s in PKCs delta, epsilon, eta, theta, phospholipases, GAPs, and perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Structure and functional interactions of the Tsg101 UEV domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ubiquitin in avian leukosis virus particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

C2-domains, structure and function of a universal Ca2+-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Monoubiquitin carries a novel internalization signal that is appended to activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Multiple WW domains, but not the C2 domain, are required for inhibition of the epithelial Na+ channel by human Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A role for ubiquitin ligase recruitment in retrovirus release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Cross-linking of cell surface immunoglobulins induces Epstein-Barr virus in Burkitt lymphoma lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A function for monoubiquitination in the internalization of a G protein-coupled receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ebola virus matrix protein VP40 interaction with human cellular factors Tsg101 and Nedd4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Structural basis for phosphoserine-proline recognition by group IV WW domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Functional domains of the Rsp5 ubiquitin-protein ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A Smad transcriptional corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

The PY-motif of Bul1 protein is essential for growth of Saccharomyces cerevisiae under various stress conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Bul1, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A HECT domain E3 enzyme assembles novel polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Mutations altering the moloney murine leukemia virus p12 Gag protein affect virion production and early events of the virus life cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Characterization of Human hect Domain Family Members and Their Interaction with UbcH5 and UbcH7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

Brief report: Liddle's syndrome revisited--a disorder of sodium reabsorption in the distal tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

7 January 2021

Membrane topology of the epithelial sodium channel in intact cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

7 January 2021

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

7 January 2021

Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

7 January 2021

Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

7 January 2021

The yeast Npi1/Rsp5 ubiquitin ligase lacking its N-terminal C2 domain is competent for ubiquitination but not for subsequent endocytosis of the gap1 permease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

7 January 2021

Converging on proline: the mechanism of WW domain peptide recognition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207436

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207436

1 reference

9 August 2017

1 reference