(Q34612524)

3 August 2017

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title

Regulation of B cell fates by BCR signaling components (English)

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3 August 2017

Tomohiro Kurosaki

1

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3 August 2017

1 June 2002

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Current Opinion in Immunology

3 August 2017

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3 August 2017

14

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3 August 2017

341-347

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3 August 2017

3

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B cell development pathways

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Autoreactivity by design: innate B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Antigen-dependent B-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Lipid rafts and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

The role of Ig beta in precursor B cell transition and allelic exclusion

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Requirement for B cell linker protein (BLNK) in B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

An essential role for BLNK in human B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Cd19-dependent activation of Akt kinase in B-lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Essential role for Gab2 in the allergic response

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

1 reference

7 January 2021

Cutting edge: B cell linker protein is dispensable for the allelic exclusion of immunoglobulin heavy chain locus but required for the persistence of CD5+ B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

CD19 and CD22 expression reciprocally regulates tyrosine phosphorylation of Vav protein during B lymphocyte signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Interaction of SLP adaptors with the SH2 domain of Tec family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

The adaptor protein BLNK is required for b cell antigen receptor-induced activation of nuclear factor-kappa B and cell cycle entry and survival of B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

PU.1/Spi-B regulation of c-rel is essential for mature B cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Ras mediates effector pathways responsible for pre-B cell survival, which is essential for the developmental progression to the late pre-B cell stage

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

The development of B cells in the bone marrow is controlled by the balance between cell-autonomous mechanisms and signals from the microenvironment.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Contribution of Receptor Editing to the Antibody Repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Cutting edge: differential sequestration of plasma membrane-associated B cell antigen receptor in mature and immature B cells into glycosphingolipid-enriched domains.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Cutting edge: B cell antigen receptor signaling occurs outside lipid rafts in immature B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Entry of B cell receptor into signaling domains is inhibited in tolerant B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

The bulk of the peripheral B-cell pool in mice is stable and not rapidly renewed from the bone marrow

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Selection events operating at various stages in B cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Impaired expansion of mouse B cell progenitors lacking Btk.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Defective B cell development and function in Btk-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Immunodeficiency in protein kinase cbeta-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Phospholipase Cgamma2 is essential in the functions of B cell and several Fc receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Cutting edge: essential role of phospholipase C-gamma 2 in B cell development and function

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Xid-like phenotypes: a B cell signalosome takes shape

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

BLNK: connecting Syk and Btk to calcium signals

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Regulation of the phospholipase C-gamma2 pathway in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Regulation of B-cell activation and differentiation by the phosphatidylinositol 3-kinase and phospholipase Cgamma pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Essential immunoregulatory role for BCAP in B cell development and function

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP)

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

IkappaB kinase alpha is essential for mature B cell development and function

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900344-8

7 January 2021

10.1016/S0952-7915(02)00344-8

Identifiers

DOI

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3 August 2017

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PubMed ID

11973132