(Q47229633)

12 January 2018

title

Cyclin-dependent kinases regulate the antiproliferative function of Smads. (English)

1 reference

12 January 2018

author name string

Isao Matsuura

1

1 reference

12 January 2018

Natalia G Denissova

2

1 reference

12 January 2018

Guannan Wang

3

1 reference

12 January 2018

Dongming He

4

1 reference

12 January 2018

Jianyin Long

5

1 reference

12 January 2018

Fang Liu

6

1 reference

12 January 2018

language of work or name

English

0 references

publication date

1 July 2004

1 reference

12 January 2018

published in

Nature

1 reference

12 January 2018

volume

430

1 reference

12 January 2018

page(s)

226-231

1 reference

12 January 2018

issue

6996

1 reference

12 January 2018

https://scigraph.springernature.com/pub.10.1038/nature02650

exact match

0 references

cites work

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

TGF-beta signaling in tumor suppression and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Transforming growth factor beta activates the promoter of cyclin-dependent kinase inhibitor p15INK4B through an Sp1 consensus site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

c-myc is a downstream target of the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Smad3 mutant mice develop metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

Assay for activity of mammalian cyclin D-dependent kinases CDK4 and CDK6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

7 January 2021

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

7 January 2021

Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine thymus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02650

7 January 2021

Identifiers

DOI

10.1038/NATURE02650

1 reference

12 January 2018

Dimensions Publication ID

0 references

1 reference

12 January 2018