(Q50290274)

English

TP53 and E2F4 bind the CDC25C gene

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6798282)

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Statements

biological process

1 reference

8 July 2022

TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-6798282

1 reference

8 July 2022

E2F4:(TFDP1,TFDP2):(RBL1,RBL2) [nucleoplasm]

1

object has role

1 reference

8 July 2022

p-S15,S20-TP53 Tetramer [nucleoplasm]

1

object has role

1 reference

8 July 2022

p-S15,S20-TP53 Tetramer:E2F4:(TFDP1,TFDP2):(RBL1,RBL2):CDC25C Gene [nucleoplasm]

1

object has role

1 reference

8 July 2022

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes

1 reference

8 July 2022

DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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