(Q33794127)

29 July 2017

title

p53-dependent gene repression through p21 is mediated by recruitment of E2F4 repression complexes (English)

1 reference

29 July 2017

E K Benson

1

1 reference

29 July 2017

S K Mungamuri

2

1 reference

29 July 2017

O Attie

3

1 reference

29 July 2017

M Kracikova

4

1 reference

29 July 2017

R Sachidanandam

5

1 reference

29 July 2017

J J Manfredi

6

1 reference

29 July 2017

S A Aaronson

7

1 reference

29 July 2017

language of work or name

English

0 references

publication date

7 October 2013

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29 July 2017

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29 July 2017

volume

33

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29 July 2017

issue

30

1 reference

29 July 2017

page(s)

3959-3969

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

29 July 2017

copyright license

start time

7 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/onc.2013.378

0 references

cites work

A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis

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p53-mediated heterochromatin reorganization regulates its cell fate decisions

4 July 2018

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Disruption of repressive p130-DREAM complexes by human papillomavirus 16 E6/E7 oncoproteins is required for cell-cycle progression in cervical cancer cells

4 July 2018

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DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly

4 July 2018

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p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor

4 July 2018

1 reference

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Wide-ranging functions of E2F4 in transcriptional activation and repression revealed by genome-wide analysis

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors.

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

The p53 pathway as a target in cancer therapeutics: obstacles and promise

4 July 2018

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Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

New insights into p53 activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

The p53 response element and transcriptional repression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Abduction and asylum in the lives of transcription factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Examination of the expanding pathways for the regulation of p21 expression and activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Emerging roles of E2Fs in cancer: an exit from cell cycle control

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Rb2/p130 is the dominating pocket protein in the p53-p21 DNA damage response pathway leading to senescence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Predicting functionality of protein-DNA interactions by integrating diverse evidence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Blinded by the Light: The Growing Complexity of p53

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Atypical E2Fs: new players in the E2F transcription factor family

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Array-based analysis of the effects of trichostatin A and CG-1521 on cell cycle and cell death in LNCaP prostate cancer cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Transcriptional control of human p53-regulated genes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Transcriptional regulation by p53: one protein, many possibilities

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Distinct E2F-mediated transcriptional program regulates p14ARF gene expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

MatInspector and beyond: promoter analysis based on transcription factor binding sites

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Tumor suppressor p53 represses transcription of RECQ4 helicase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Opposing roles of E2Fs in cell proliferation and death

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

E2Fs link the control of G1/S and G2/M transcription

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

p53-dependent down-regulation of telomerase is mediated by p21waf1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Transcriptional repression by p53 promotes a Bcl-2-insensitive and mitochondria-independent pathway of apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

The role of p53 in chemosensitivity and radiosensitivity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

p21/CDKN1A mediates negative regulation of transcription by p53.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Transcriptional repression mediated by the p53 tumour suppressor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

p53-Mdm2--the affair that never ends

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

DNA microarrays identification of primary and secondary target genes regulated by p53.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

p53 down-regulates CHK1 through p21 and the retinoblastoma protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Target gene specificity of E2F and pocket protein family members in living cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

CDK inhibitors: positive and negative regulators of G1-phase progression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067464

Structural basis of DNA recognition by p53 tetramers.

4 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Negative regulation of Chk2 expression by p53 is dependent on the CCAAT-binding transcription factor NF-Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Activated p53 suppresses the histone methyltransferase EZH2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Genome-wide analysis of p53 under hypoxic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

Effect of restoration of retinoblastoma gene function on the radiosensitivity of cells of human tumor cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.378

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.378

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference