(Q50335767)

5 March 2018

title

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53. (English)

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5 March 2018

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5

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author name string

William H Hoffman

1

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5 March 2018

Siham Biade

2

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5 March 2018

Jack T Zilfou

3

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5 March 2018

Jiandong Chen

4

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5 March 2018

language of work or name

English

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publication date

19 November 2001

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5 March 2018

Journal of Biological Chemistry

published in

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volume

277

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issue

5

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5 March 2018

page(s)

3247-3257

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5 March 2018

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

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Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting

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Control of apoptosis and mitotic spindle checkpoint by survivin

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Transcriptional analysis of human survivin gene expression

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Pleiotropic cell-division defects and apoptosis induced by interference with survivin function

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Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division

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Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis.

21 January 2018

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21 January 2018

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p53, the cellular gatekeeper for growth and division

21 January 2018

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Wild-type p53 negatively regulates the expression of a microtubule-associated protein

21 January 2018

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Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression

21 January 2018

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

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Identification of a novel p53 functional domain that is necessary for efficient growth suppression

21 January 2018

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The polyproline region of p53 is required to activate apoptosis but not growth arrest.

21 January 2018

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The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

21 January 2018

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Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

21 January 2018

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The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation

21 January 2018

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Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

21 January 2018

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p53 regulates a G2 checkpoint through cyclin B1

21 January 2018

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p130/E2F4 binds to and represses the cdc2 promoter in response to p53.

21 January 2018

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NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

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Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells

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21 January 2018

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The p53-mdm-2 autoregulatory feedback loop

21 January 2018

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Temperature-sensitive mutants of p53 homologs

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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Binding of a simian virus 40 T antigen-related protein to DNA

21 January 2018

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Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells

21 January 2018

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The mdm-2 gene is induced in response to UV light in a p53-dependent manner

21 January 2018

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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

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p53 tagged sites from human genomic DNA.

21 January 2018

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Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

21 January 2018

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CDF-1, a novel E2F-unrelated factor, interacts with cell cycle-regulated repressor elements in multiple promoters.

21 January 2018

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p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor

21 January 2018

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p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding

21 January 2018

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Definition of a consensus binding site for p53

21 January 2018

1 reference

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Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106643200

Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106643200

Transcriptional repression by p53 through direct binding to a novel DNA element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106643200

The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106643200

21 January 2018

Identifiers

DOI

10.1074/JBC.M106643200

1 reference

5 March 2018

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5 March 2018