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Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
title
Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author
Kevin M Ryan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
author name string
K H Vousden
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
language of work or name
English
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publication date
1 July 1998
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Molecular and Cellular Biology
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
18
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
3692-3698
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.
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Regulation of p53 stability by Mdm2
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Mdm2 promotes the rapid degradation of p53
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PubMed Central
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bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
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4 July 2018
p53, the cellular gatekeeper for growth and division
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Bax suppresses tumorigenesis and stimulates apoptosis in vivo
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Wild-type p53 negatively regulates the expression of a microtubule-associated protein
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PubMed Central
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4 July 2018
p53 in signaling checkpoint arrest or apoptosis
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PubMed Central
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4 July 2018
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
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PubMed Central
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4 July 2018
Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function
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PubMed Central
reference URL
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4 July 2018
Genetic determinants of p53-induced apoptosis and growth arrest
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PubMed Central
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4 July 2018
p53: puzzle and paradigm
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4 July 2018
Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant
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4 July 2018
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
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4 July 2018
An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription
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4 July 2018
Sequence-specific transcriptional activation is essential for growth suppression by p53.
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PubMed Central
reference URL
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4 July 2018
Modulation of transcriptional regulatory properties of p53 by HPV E6.
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4 July 2018
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein
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4 July 2018
Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.
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4 July 2018
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
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4 July 2018
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
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4 July 2018
Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.
1 reference
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PubMed Central
reference URL
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4 July 2018
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
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PubMed Central
reference URL
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4 July 2018
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4 July 2018
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
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4 July 2018
Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
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4 July 2018
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
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PubMed Central
reference URL
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4 July 2018
p21 is necessary for the p53-mediated G1 arrest in human cancer cells
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PubMed Central
reference URL
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4 July 2018
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
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PubMed Central
reference URL
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4 July 2018
Induction of the growth inhibitor IGF-binding protein 3 by p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
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4 July 2018
Radiation-induced cell cycle arrest compromised by p21 deficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
4 July 2018
Wild-type p53 can down-modulate the activity of various promoters
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
4 July 2018
Cancer. p53, guardian of the genome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
4 July 2018
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
4 July 2018
Inhibition of viral and cellular promoters by human wild-type p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
4 July 2018
Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
30 October 2018
Transcriptional activation by p53 correlates with suppression of growth but not transformation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
30 October 2018
Induction of apoptosis in HeLa cells by trans-activation-deficient p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108951
retrieved
30 October 2018
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9632751
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9632751
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9632751
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
p53-dependent apoptosis suppresses tumor growth and progression in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9632751
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.18.7.3692
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PMC publication ID
108951
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
PubMed publication ID
9632751
1 reference
stated in
Europe PubMed Central
PMC publication ID
108951
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9632751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
ResearchGate publication ID
13651337
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