(Q39817833)

14 September 2017

Rb2/p130 is the dominating pocket protein in the p53-p21 DNA damage response pathway leading to senescence (English)

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14 September 2017

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H Helmbold

1

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14 September 2017

N Kömm

series ordinal

2

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14 September 2017

W Deppert

series ordinal

3

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14 September 2017

W Bohn

series ordinal

4

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14 September 2017

language of work or name

English

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publication date

3 August 2009

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14 September 2017

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14 September 2017

28

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14 September 2017

39

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14 September 2017

3456-3467

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https://scigraph.springernature.com/pub.10.1038/onc.2009.222

14 September 2017

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cites work

Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

The DNA damage signaling pathway connects oncogenic stress to cellular senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

The transcription factor E2F-1 mediates the autoregulation of RB gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Distinct recruitment of E2F family members to specific E2F-binding sites mediates activation and repression of the E2F1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Reversal of human cellular senescence: roles of the p53 and p16 pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Oncogene-induced senescence as an initial barrier in lymphoma development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Tumor-specific exon 1 mutations could be the 'hit event' predisposing Rb2/p130 gene to epigenetic silencing in lung cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Cell cycle-specific association of E2F with the p130 E1A-binding protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Tumour biology: senescence in premalignant tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Regulation of cellular senescence by Rb2/p130.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Cooperation between p53 and p130(Rb2) in induction of cellular senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Cancer risk and the ATM gene: a continuing debate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Identification of a p130 domain mediating interactions with cyclin A/cdk 2 and cyclin E/cdk 2 complexes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Expression of Rb2/p130 protein correlates with the degree of malignancy in gliomas.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

To cycle or not to cycle: a critical decision in cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

The IARC TP53 database: new online mutation analysis and recommendations to users

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

A Restriction Point for Control of Normal Animal Cell Proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Expression of the retinoblastoma-related gene Rb2/p130 is downregulated in atypical endometrial hyperplasia and adenocarcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

The E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.222

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.222

1 reference

14 September 2017

1 reference