(Q36579261)

15 August 2017

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title

Regulation of cellular senescence by Rb2/p130. (English)

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15 August 2017

Helmbold H

1

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15 August 2017

Deppert W

series ordinal

2

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15 August 2017

Bohn W

series ordinal

3

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15 August 2017

language of work or name

English

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publication date

1 August 2006

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15 August 2017

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15 August 2017

25

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15 August 2017

38

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15 August 2017

5257-5262

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209613

15 August 2017

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cites work

Functional interactions between the hBRM/hBRG1 transcriptional activators and the pRB family of proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Distinct recruitment of E2F family members to specific E2F-binding sites mediates activation and repression of the E2F1 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Genomic structure of the human retinoblastoma-related Rb2/p130 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cycle regulated

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Reversal of human cellular senescence: roles of the p53 and p16 pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Oncogene-induced senescence as an initial barrier in lymphoma development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Direct transcriptional repression by pRB and its reversal by specific cyclins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Requirements for cell cycle arrest by p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

From cells to organisms: can we learn about aging from cells in culture?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Phosphorylation of the retinoblastoma-related protein p130 in growth-arrested cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Combinatorial roles for pRB, p107, and p130 in E2F-mediated cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Pocket proteins and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Cyclin A repression in quiescent cells is associated with chromatin remodeling of its promoter and requires Brahma/SNF2alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Frequent loss of pRb2/p130 in human ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The role of cyclin D3-dependent kinase in the phosphorylation of p130 in mouse BALB/c 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Physical interaction of the retinoblastoma protein with human D cyclins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

A viral mechanism for remodeling chromatin structure in G0 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Structure of the human retinoblastoma gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Structure of the human retinoblastoma-related p107 gene and its intragenic deletion in a B-cell lymphoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Cooperation between p53 and p130(Rb2) in induction of cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Identification of a p130 domain mediating interactions with cyclin A/cdk 2 and cyclin E/cdk 2 complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

E2F4 loss suppresses tumorigenesis in Rb mutant mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Human retinoblastoma susceptibility gene: cloning, identification, and sequence.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Expression of Rb2/p130 protein correlates with the degree of malignancy in gliomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Regulation of neuron survival and death by p130 and associated chromatin modifiers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Specific enzymatic dephosphorylation of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Genetic and epigenetic alterations as hallmarks of the intricate road to cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Expression of Rb2/p130 in breast and endometrial cancer: correlations with hormone receptor status

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Balance between acetylation and methylation of histone H3 lysine 9 on the E2F-responsive dihydrofolate reductase promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

G1 events and regulation of cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The transcription factor E2F-1 mediates the autoregulation of RB gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Negative regulation of Rb expression by the p53 gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

p16/MTS1/INK4A suppresses prostate cancer by both pRb dependent and independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

BRG-1 is required for RB-mediated cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Expression of the retinoblastoma-related gene Rb2/p130 is downregulated in atypical endometrial hyperplasia and adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Re-expression of endogenous p16ink4a in oral squamous cell carcinoma lines by 5-aza-2'-deoxycytidine treatment induces a senescence-like state

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209613

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209613

1 reference

Dimensions Publication ID

15 August 2017

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1 reference