(Q54021692)

23 May 2018

title

Escape from premature senescence is not sufficient for oncogenic transformation by Ras. (English)

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23 May 2018

author

René Bernards

5

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author name string

Peeper DS

1

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23 May 2018

Dannenberg JH

2

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23 May 2018

Douma S

3

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23 May 2018

te Riele H

4

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23 May 2018

publication date

1 February 2001

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23 May 2018

published in

Nature Cell Biology

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23 May 2018

volume

3

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23 May 2018

issue

2

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23 May 2018

page(s)

198-203

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23 May 2018

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

cites work

1 reference

7 January 2021

In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.

1 reference

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

7 January 2021

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

1 reference

7 January 2021

The cat and mouse games that genes, viruses, and cells play

1 reference

7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1 reference

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

7 January 2021

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

7 January 2021

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

1 reference

7 January 2021

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

1 reference

7 January 2021

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

1 reference

7 January 2021

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

1 reference

7 January 2021

Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation

1 reference

7 January 2021

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

1 reference

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

1 reference

7 January 2021

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs

1 reference

7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

1 reference

7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

7 January 2021

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

1 reference

7 January 2021

Distinct roles for cyclin-dependent kinases in cell cycle control

1 reference

7 January 2021

Identifiers

DOI

10.1038/35055110

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23 May 2018

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23 May 2018