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English
E2F4 loss suppresses tumorigenesis in Rb mutant mice.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
title
E2F4 loss suppresses tumorigenesis in Rb mutant mice
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
author
Joseph Rayman
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
author name string
Eunice Y Lee
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
Hieu Cam
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
Ulrike Ziebold
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
Jacqueline A Lees
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
Brian David Dynlacht
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
publication date
1 December 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
published in
Cancer Cell
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
volume
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
page(s)
463-472
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
cites work
Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein pathway and the restriction point
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shared role of the pRB-related p130 and p107 proteins in limb development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linking the Rb and polycomb pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for E2F proteins in cell growth control and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of E2F by pRB-family proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F4 is exported from the nucleus in a CRM1-dependent manner.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4, a new member of the E2F transcription factor family, interacts with p107
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell proliferation by the E2F transcription factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the retinoblastoma protein-related p130 protein in small cell lung carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-5, a new E2F family member that interacts with p130 in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F4 is essential for normal erythrocyte maturation and neonatal viability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of an Rb mutation in the mouse
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of p107: functional overlap between p107 and Rb
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene family: cousins with overlapping interests.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p107 is a suppressor of retinoblastoma development in pRb-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer cell cycles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sibling rivalry in the E2F family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F activity is regulated by cell cycle-dependent changes in subcellular localization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E2F1-3 transcription factors are essential for cellular proliferation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900207-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1535-6108(02)00207-6
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
PubMed ID
12498715
1 reference
stated in
Europe PubMed Central
PubMed ID
12498715
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12498715%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 December 2019
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