(Q74428375)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9537419%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9537419%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

3

1 reference

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10 November 2019

author name string

Yamasaki L

1

1 reference

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10 November 2019

Bronson R

2

1 reference

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10 November 2019

Dyson NJ

4

1 reference

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10 November 2019

Harlow E

5

1 reference

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10 November 2019

Jacks T

6

1 reference

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10 November 2019

publication date

1 April 1998

1 reference

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10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9537419%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

18

1 reference

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10 November 2019

page(s)

360-364

1 reference

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10 November 2019

issue

4

1 reference

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https://scigraph.springernature.com/pub.10.1038/ng0498-360

10 November 2019

exact match

0 references

cites work

The retinoblastoma protein: more than a tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Effects of an Rb mutation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

https://api.crossref.org/works/10.1038%2FNG0498-360

1 reference

7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Oncogenic capacity of the E2F1 gene

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Multiple members of the E2F transcription factor family are the products of oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Requirement for a functional Rb-1 gene in murine development

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNG0498-360

7 January 2021

Identifiers

DOI

10.1038/NG0498-360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9537419%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference