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MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8937097)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
part of
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
exact match
https://identifiers.org/reactome:R-HSA-8937097
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
has part(s)
miR-27a Nonendonucleolytic RISC [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
cites work
Histone arginine methylation keeps RUNX1 target genes in an intermediate state
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
Identifiers
Reactome ID
R-HSA-8937097
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8937097
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