(Q50291232)

English

Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin.

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5602080)

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biological process

1 reference

8 July 2022

Common Pathway of Fibrin Clot Formation

1 reference

13 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5602080

1 reference

8 July 2022

activated thrombin (factor IIa) [plasma membrane]

1

object of statement has role

1 reference

8 July 2022

SERPINE2:GAG [plasma membrane]

1

object of statement has role

1 reference

8 July 2022

SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane]

1

object of statement has role

1 reference

8 July 2022

Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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