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English
Activation of Vav1
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-389354)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
part of
CD28 dependent Vav1 pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
exact match
https://identifiers.org/reactome:R-HSA-389354
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
has part(s)
ATP(4-)
quantity
3
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
VAV1:PIP3:CD28:GRB2 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
ADP(3-)
quantity
3
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
p-Y142,160,174-VAV1:PIP3:CD28:GRB2 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
FYN proto-oncogene, Src family tyrosine kinase
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
cites work
Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
Vav-family proteins in T-cell signalling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
Vav1: a key signal transducer downstream of the TCR
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
Identifiers
Reactome ID
R-HSA-389354
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-389354
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