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(Q50291486)
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TRPC1 translocates calcium from the extracellular region to the cytosol
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2089943)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
part of
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
Ion homeostasis
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
exact match
https://identifiers.org/reactome:R-HSA-2089943
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
has part(s)
calcium(2+)
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
calcium(2+)
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
STIM1:TRPC1 [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
cites work
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
Identifiers
Reactome ID
R-HSA-2089943
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2089943
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