(Q50291711)

English

3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5684273)

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Statements

biological process

1 reference

8 July 2022

MAP3K8 (TPL2)-dependent MAPK1/3 activation

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5684273

1 reference

8 July 2022

3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol]

1

object has role

1 reference

8 July 2022

p-S400,T290-MAP3K8 [cytosol]

1

object has role

1 reference

8 July 2022

TNFAIP3 interacting protein 2

1

object has role

1 reference

8 July 2022

9

object has role

1 reference

8 July 2022

IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400

1 reference

8 July 2022

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

1 reference

8 July 2022

NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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