(Q50291812)

English

IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-166091)

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Statements

1 reference

8 July 2022

MyD88:MAL(TIRAP) cascade initiated on plasma membrane

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-166091

1 reference

8 July 2022

IRAK1, IRAK2 [cytosol]

quantity

4

object of statement has role

1 reference

8 July 2022

p-S,2T-IRAK4:oligo-MyD88:TIRAP:activated TLR receptor [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

IRAK1/or IRAK2:p-IRAK4:MyD88 oligomer:TIRAP:activated TLR [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

Human interleukin-1 receptor-associated kinase-2 is essential for Toll-like receptor-mediated transcriptional and post-transcriptional regulation of tumor necrosis factor alpha

1 reference

8 July 2022

IRAK1: a critical signaling mediator of innate immunity

1 reference

8 July 2022

Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control.

1 reference

8 July 2022

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

1 reference

8 July 2022

IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination

1 reference

8 July 2022

A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50291812)

IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex

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