(Q50292563)

English

Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-452108)

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Statements

biological process

1 reference

8 July 2022

Interleukin-2 signaling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-452108

1 reference

8 July 2022

IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3 [plasma membrane]

1

object has role

1 reference

8 July 2022

STAT5A,STAT5B [cytosol]

1

object has role

1 reference

8 July 2022

IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5 [plasma membrane]

1

object has role

1 reference

8 July 2022

Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity

1 reference

8 July 2022

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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