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Phosphorylated SHC recruits GRB2:SOS1
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-453111)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
part of
Interleukin receptor SHC signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
exact match
https://identifiers.org/reactome:R-HSA-453111
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
has part(s)
GRB2-1:SOS1 [cytosol]
quantity
4
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
Interleukin receptor complexes with activated SHC1 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
Interleukin receptor complexes with activated SHC1:GRB2:SOS1 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
cites work
Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
Identifiers
Reactome ID
R-HSA-453111
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-453111
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