(Q50292616)

English

JAK2 is phosphorylated, activated

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-879910)

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8 July 2022

Interleukin-3, Interleukin-5 and GM-CSF signaling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-879910

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8 July 2022

6

object of statement has role

1 reference

8 July 2022

High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

6

object of statement has role

1 reference

8 July 2022

High affinity binding complex dimers of cytokine receptors using Bc, activated JAK2 [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2 [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

1 reference

8 July 2022

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50292616)

JAK2 is phosphorylated, activated

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