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SHC1 bound to the common beta chain becomes tyrosine phosphorylated
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-879925)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
part of
Interleukin-3, Interleukin-5 and GM-CSF signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
exact match
https://identifiers.org/reactome:R-HSA-879925
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
has part(s)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p-(Y593,628)-Bc:p(427,349,350)-SHC1 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
cites work
A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
Tyrosine phosphorylation of Shc is induced by IL-3, IL-5 and GM-CSF.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
Identifiers
Reactome ID
R-HSA-879925
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879925
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