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CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-879917)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
part of
Regulation of signaling by CBL
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
exact match
https://identifiers.org/reactome:R-HSA-879917
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
has part(s)
cbl proto-oncogene
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
FYN-like kinases [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
Growth factor receptor bound protein 2
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
p85-containing Class 1A PI3Ks [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
cites work
CBL-GRB2 interaction in myeloid immunoreceptor tyrosine activation motif signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
Phosphorylation of cbl after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
Identifiers
Reactome ID
R-HSA-879917
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-879917
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