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PGH2 is reduced to PGF2a by AKR1C3
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2161549)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
part of
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
exact match
https://identifiers.org/reactome:R-HSA-2161549
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
has part(s)
hydron
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
prostaglandin H2
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
prostaglandin F2α
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
aldo-keto reductase family 1 member C3
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
NADPH(4-)
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
NADP(3-)
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
cites work
cDNA cloning, expression and characterization of human prostaglandin F synthase
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
Crystal structure of human prostaglandin F synthase (AKR1C3)
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
Prostaglandin F2alpha formation from prostaglandin H2 by prostaglandin F synthase (PGFS): crystal structure of PGFS containing bimatoprost
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
Identifiers
Reactome ID
R-HSA-2161549
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2161549
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