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PTHP is reduced to BH4 by sepiapterin reductase (SPR)
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1475414)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
part of
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
exact match
https://identifiers.org/reactome:R-HSA-1475414
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
has part(s)
dyspropterin
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
5,6,7,8-tetrahydrobiopterin
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
p-SPR dimer [cytosol]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
NADPH(4-)
quantity
2
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
NADP(3-)
quantity
2
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
cites work
Cloning and sequencing of cDNA encoding human sepiapterin reductase--an enzyme involved in tetrahydrobiopterin biosynthesis
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
Identifiers
Reactome ID
R-HSA-1475414
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1475414
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