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(Q50295904)
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ELAC2 cleaves the 3' end of pre-tRNA
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5696815)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
tRNA 3'-end processing
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
part of
tRNA processing in the nucleus
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
exact match
https://identifiers.org/reactome:R-HSA-5696815
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
has part(s)
5' cleaved pre-tRNA [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
5',3' cleaved pre-tRNA [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
ElaC ribonuclease Z 2
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
cites work
Involvement of human ELAC2 gene product in 3' end processing of mitochondrial tRNAs
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
Localization of human RNase Z isoforms: dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
Functional analyses for tRNase Z variants: an aspartate and a histidine in the active site are essential for the catalytic activity
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
The N-terminal half-domain of the long form of tRNase Z is required for the RNase 65 activity
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
Naturally occurring mutations in human mitochondrial pre-tRNASer(UCN) can affect the transfer ribonuclease Z cleavage site, processing kinetics, and substrate secondary structure
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
Identifiers
Reactome ID
R-HSA-5696815
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5696815
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