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Indirect recruitment of GAB2 to p-KIT
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-205234)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
part of
Signaling by SCF-KIT
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
exact match
https://identifiers.org/reactome:R-HSA-205234
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
has part(s)
GRB2 associated binding protein 2
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
GRB2:p-SHP2:p-KIT complex [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
cites work
Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
The scaffolding adapter Gab2, via Shp-2, regulates kit-evoked mast cell proliferation by activating the Rac/JNK pathway.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
Identifiers
Reactome ID
R-HSA-205234
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-205234
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