(Q50297981)

English

Recruitment of CBL to KIT

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-205244)

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Statements

biological process

1 reference

8 July 2022

Regulation of KIT signaling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-205244

1 reference

8 July 2022

cbl proto-oncogene

1

object has role

1 reference

8 July 2022

Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane]

1

object has role

1 reference

8 July 2022

CBL:Grb2/p-APS:p-c-Kit complex [plasma membrane]

1

object has role

1 reference

8 July 2022

The Cbl family of ubiquitin ligases: critical negative regulators of tyrosine kinase signaling in the immune system

1 reference

8 July 2022

Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation.

1 reference

8 July 2022

The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit

1 reference

8 July 2022

Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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