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USP8 deubiquitinates FZD to potentiate WNT signaling
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-4641236)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
part of
Regulation of FZD by ubiquitination
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
exact match
https://identifiers.org/reactome:R-HSA-4641236
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
has part(s)
water
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
Ub [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
Ubiquitin specific peptidase 8
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
cites work
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
Identifiers
Reactome ID
R-HSA-4641236
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-4641236
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