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VLDLR:PCSK9 binds Clathrin-coated vesicles
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8855131)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
part of
VLDLR internalisation and degradation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
exact match
https://identifiers.org/reactome:R-HSA-8855131
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
has part(s)
Clathrin:AP-2 complex [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
VLDL:PCSK9 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
VLDL:PCSK9:Clathrin:AP2 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
cites work
The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
Identifiers
Reactome ID
R-HSA-8855131
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-8855131
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