(Q50299811)

English

VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8855130)

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Statements

biological process

1 reference

8 July 2022

VLDLR internalisation and degradation

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-8855130

1 reference

8 July 2022

VLDL:PCSK9:Clathrin:AP2 [plasma membrane]

1

object has role

1 reference

8 July 2022

VLDL:PCSK9:Clathrin:AP2 [lysosomal membrane]

1

object has role

1 reference

8 July 2022

The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2

1 reference

8 July 2022

Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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