(Q50299950)

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Endophilins recruit synaptojanins to the clathrin-coated pit

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8868651)

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8 July 2022

Clathrin-mediated endocytosis

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-8868651

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8 July 2022

PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane]

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8 July 2022

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8 July 2022

PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]

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8 July 2022

Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15

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8 July 2022

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

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8 July 2022

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

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8 July 2022

Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size

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8 July 2022

A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism

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8 July 2022

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

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8 July 2022

Inositol lipid phosphatases in membrane trafficking and human disease.

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8 July 2022

Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating

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8 July 2022

Dap160/intersectin scaffolds the periactive zone to achieve high-fidelity endocytosis and normal synaptic growth.

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8 July 2022

Molecular circuitry of endocytosis at nerve terminals.

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8 July 2022

Synaptojanin 1-mediated PI(4,5)P2 hydrolysis is modulated by membrane curvature and facilitates membrane fission

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8 July 2022

A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis

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8 July 2022

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages

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8 July 2022

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

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8 July 2022

BAR domain scaffolds in dynamin-mediated membrane fission

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8 July 2022

The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity

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8 July 2022

All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis

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8 July 2022

Recruitment of endophilin to clathrin-coated pit necks is required for efficient vesicle uncoating after fission

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8 July 2022

Endophilin Is Required for Synaptic Vesicle Endocytosis by Localizing Synaptojanin

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50299950)

Endophilins recruit synaptojanins to the clathrin-coated pit

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