(Q38223317)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Inositol lipid phosphatases in membrane trafficking and human disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Martin Lowe

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

language of work or name

English

0 references

publication date

1 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

461

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

159-175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

Phosphoinositides in cell regulation and membrane dynamics

21 March 2020

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Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate

21 January 2018

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Mutations in phosphoinositide metabolizing enzymes and human disease

21 January 2018

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The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

21 January 2018

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Phosphoinositide phosphatases in cell biology and disease

21 January 2018

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Phosphatidylinositol-4-phosphate: the Golgi and beyond

21 January 2018

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Molecular mechanism and physiological functions of clathrin-mediated endocytosis

21 January 2018

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Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate

21 January 2018

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Lipid metabolism and dynamics during phagocytosis

21 January 2018

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Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2.

21 January 2018

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Myotubularin phosphoinositide phosphatases: cellular functions and disease pathophysiology

21 January 2018

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Loss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafish

21 January 2018

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Sequential actions of myotubularin lipid phosphatases regulate endosomal PI(3)P and growth factor receptor trafficking

21 January 2018

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Myotubularin lipid phosphatase binds the hVPS15/hVPS34 lipid kinase complex on endosomes

21 January 2018

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The phosphoinositide 3-phosphatase MTMR2 interacts with PSD-95 and maintains excitatory synapses by modulating endosomal traffic

21 January 2018

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Endosomal targeting of the phosphoinositide 3-phosphatase MTMR2 is regulated by an N-terminal phosphorylation site

21 January 2018

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Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

21 January 2018

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Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway

21 January 2018

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Functional redundancy in the myotubularin family

21 January 2018

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Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport

21 January 2018

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Drosophila Mtm and class II PI3K coregulate a PI(3)P pool with cortical and endolysosomal functions

21 January 2018

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Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance

21 January 2018

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The myotubularin phosphatase MTMR4 regulates sorting from early endosomes

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20140361

MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20140361

MTM1 mutations in X-linked myotubular myopathy

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20140361

The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

21 January 2018

1 reference

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Wrapping it up: the cell biology of myelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.

21 January 2018

1 reference

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Mutation of the SBF2 gene, encoding a novel member of the myotubularin family, in Charcot-Marie-Tooth neuropathy type 4B2/11p15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The role of lipids in the control of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The role of PI3P phosphatases in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Phosphatidylinositol-3-phosphate clearance plays a key role in autophagosome completion

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

PTEN controls immunoreceptor (immunoreceptor tyrosine-based activation motif) signaling and the activation of Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

INPP4A/INPP4B and P-Rex proteins: related but different?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane

21 January 2018

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An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Patterned neuroprotection in the Inpp4a(wbl) mutant mouse cerebellum correlates with the expression of Eaat4

21 January 2018

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22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia

21 January 2018

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A new trick of INPP4A: decreased expression of INPP4A in patients with temporal lobe epilepsy and pilocarpine-induced rat model

21 January 2018

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Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Characterization of the murine Inpp4b gene and identification of a novel isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Phosphoinositide 3-kinase and INPP4B in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Dent Disease with mutations in OCRL1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Inositol 5-phosphatases: insights from the Lowe syndrome protein OCRL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The cellular and physiological functions of the Lowe syndrome protein OCRL1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Type II phosphoinositide 5-phosphatases have unique sensitivities towards fatty acid composition and head group phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Lowe syndrome protein OCRL1 interacts with clathrin and regulates protein trafficking between endosomes and the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

OCRL controls trafficking through early endosomes via PtdIns4,5P₂-dependent regulation of endosomal actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Impaired neural development in a zebrafish model for Lowe syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Regulation of phagocytosis in Dictyostelium by the inositol 5-phosphatase OCRL homolog Dd5P4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Rab35 GTPase and OCRL phosphatase remodel lipids and F-actin for successful cytokinesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The inositol 5-phosphatase dOCRL controls PI(4,5)P2 homeostasis and is necessary for cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Lowe Syndrome protein OCRL1 supports maturation of polarized epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The Lowe syndrome protein OCRL1 is involved in primary cilia assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

OCRL1 modulates cilia length in renal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Sertoli cell vacuolization and abnormal germ cell adhesion in mice deficient in an inositol polyphosphate 5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Tissue-specific alternative splicing generates two synaptojanin isoforms with differential membrane binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Molecular cloning of multiple isoforms of synaptojanin 2 and assignment of the gene to mouse chromosome 17A2-3.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

A presynaptic inositol-5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Mutations in synaptojanin disrupt synaptic vesicle recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Excessive expression of synaptojanin in brains with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Trisomy for synaptojanin1 in Down syndrome is functionally linked to the enlargement of early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20140361

Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Reduction of synaptojanin 1 accelerates Aβ clearance and attenuates cognitive deterioration in an Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The Sac1 domain of SYNJ1 identified mutated in a family with early-onset progressive Parkinsonism with generalized seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Synaptojanin 2 functions at an early step of clathrin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Synaptojanin 2, a novel Rac1 effector that regulates clathrin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Cloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

s-SHIP promoter expression marks activated stem cells in developing mouse mammary tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

21 January 2018

Role of SHIP in cancer

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Differential association of phosphatidylinositol 3-kinase, SHIP-1, and PTEN with forming phagosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The SH2 domain-containing 5-phosphatase SHIP2 is expressed in the germinal layers of embryo and adult mouse brain: increased expression in N-CAM-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The inositol 5-phosphatase SHIP2 is an effector of RhoA and is involved in cell polarity and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

SH2-containing 5'-inositol phosphatase, SHIP2, regulates cytoskeleton organization and ligand-dependent down-regulation of the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The inositol phosphatase SHIP-2 down-regulates FcgammaR-mediated phagocytosis in murine macrophages independently of SHIP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

SHIP2 and its involvement in various diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Identification and characterization of a novel inositol polyphosphate 5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Novel inositol polyphosphate 5-phosphatase localizes at membrane ruffles

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Requirement of phosphatidylinositol(3,4,5)trisphosphate in phosphatidylinositol 3-kinase-induced oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20140361

Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1.

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20140361

Spatial regulation of Golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

rSac3, a novel Sac domain phosphoinositide phosphatase, promotes neurite outgrowth in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

PIKfyve regulation of endosome-linked pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Fig4 deficiency: a newly emerged lysosomal storage disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Mutation of FIG4 causes a rapidly progressive, asymmetric neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

ALS-associated protein FIG4 is localized in Pick and Lewy bodies, and also neuronal nuclear inclusions, in polyglutamine and intranuclear inclusion body diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Pathogen trafficking pathways and host phosphoinositide metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Manipulation of host membranes by bacterial effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Enteropathogenic Escherichia coli recruits the cellular inositol phosphatase SHIP2 to regulate actin-pedestal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Yersinia entry into host cells requires Rab5-dependent dephosphorylation of PI(4,5)P₂ and membrane scission

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Multiple host proteins that function in phosphatidylinositol-4-phosphate metabolism are recruited to the chlamydial inclusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Phosphatidylinositol 5-phosphatase oculocerebrorenal syndrome of Lowe protein (OCRL) controls actin dynamics during early steps of Listeria monocytogenes infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

A synaptojanin-homologous region of Salmonella typhimurium SigD is essential for inositol phosphatase activity and Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Salmonella modulates vesicular traffic by altering phosphoinositide metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Phosphoinositide signaling: new tools and insights.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Optogenetic control of phosphoinositide metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Production of phosphatidylinositol 5-phosphate by the phosphoinositide 3-phosphatase myotubularin in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Type I phosphatidylinositol-4,5-bisphosphate 4-phosphatase regulates stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Modulation of local PtdIns3P levels by the PI phosphatase MTMR3 regulates constitutive autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140361

21 January 2018

Identifiers

DOI

10.1042/BJ20140361

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966051%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference