(Q27861051)

Receptors and phosphoinositide-generated second messengers

ChEBI release 2020-05-28

2

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author name string

Gilbert Di Paolo

series ordinal

1

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language of work or name

English

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publication date

12 October 2006

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published in

Nature

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volume

443

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issue

7112

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page(s)

651-7

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cites work

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7 January 2021

Inositol phosphates and cell signalling

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Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

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Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts

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Phosphoinositide regulation of the actin cytoskeleton

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Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

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7 January 2021

An inositol tetrakisphosphate-containing phospholipid in activated neutrophils

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7 January 2021

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP.

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Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

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7 January 2021

A presynaptic inositol-5-phosphatase

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7 January 2021

Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking

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7 January 2021

Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis

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7 January 2021

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

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7 January 2021

Phosphoinositide recognition domains

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7 January 2021

Inositol-lipid binding motifs: signal integrators through protein-lipid and protein-protein interactions

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7 January 2021

The role of phosphatases in inositol signaling reactions

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7 January 2021

Phosphoinositide signaling and the regulation of membrane trafficking in yeast

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7 January 2021

Phosphoinositides in constitutive membrane traffic.

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7 January 2021

Subcellular targeting by membrane lipids

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7 January 2021

Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: insights from vesicle recycling in nerve terminals

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7 January 2021

Organelle identity and the signposts for membrane traffic

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7 January 2021

Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits

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7 January 2021

Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi

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7 January 2021

Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2.

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7 January 2021

Adaptors for clathrin coats: structure and function.

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7 January 2021

Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation

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7 January 2021

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

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7 January 2021

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

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7 January 2021

The phosphoinositide 3-kinase pathway

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7 January 2021

Dynamics of phosphoinositides in membrane retrieval and insertion

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7 January 2021

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

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7 January 2021

PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease

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7 January 2021

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

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7 January 2021

Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate

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7 January 2021

Cellular motility driven by assembly and disassembly of actin filaments

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7 January 2021

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

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7 January 2021

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex

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7 January 2021

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Temporal and spatial regulation of chemotaxis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

PI(4,5)P2-dependent microdomain assemblies capture microtubules to promote and control leading edge motility

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

The lipid binding pleckstrin homology domain in UNC-104 kinesin is necessary for synaptic vesicle transport in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

The protein machinery of vesicle budding and fusion

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Facilitation of synaptic transmission by EGL-30 Gqalpha and EGL-8 PLCbeta: DAG binding to UNC-13 is required to stimulate acetylcholine release

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Actin Assembly and Endocytosis: From Yeast to Mammals

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Subversion of phosphoinositide metabolism by intracellular bacterial pathogens

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

ARF is required for maintenance of yeast Golgi and endosome structure and function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

The role of the phosphoinositides at the Golgi complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Rab proteins as membrane organizers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Plasma membrane phosphoinositide organization by protein electrostatics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

Oncogenic PI3K deregulates transcription and translation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021

An emerging role for PtdIns(4,5)P2-mediated signalling in human disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05185

7 January 2021