(Q50335770)

English

The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21(CIP1/Waf1).

scientific article published in September 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

The Brn-3a transcription factor inhibits the pro-apoptotic effect of p53 and enhances cell cycle arrest by differentially regulating the activity of the p53 target genes encoding Bax and p21(CIP1/Waf1). (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

apoptotic process

1 reference

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author name string

Vishwanie Budram-Mahadeo

1

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

Peter J Morris

2

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

David S Latchman

3

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

language of work or name

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publication date

1 September 2002

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

21

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

39

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

6123-6131

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

The DNA target site for the Brn-3 POU family transcription factors can confer responsiveness to cyclic AMP and removal of serum in neuronal cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

p53 plays a regulatory role in differentiation and apoptosis of central nervous system-associated cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors

1 reference

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21 January 2018

Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Expression of a large family of POU-domain regulatory genes in mammalian brain development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

A role for the tumour suppressor gene p53 in regulating neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Heat shock protein-56 is induced by cardiotrophin-1 and mediates its hypertrophic effect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

POU domain family values: flexibility, partnerships, and developmental codes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Apoptosis in neurological disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Growth factor synergism and antagonism in early neural crest development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

POU domain transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Novel cell lines display properties of nociceptive sensory neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

21 January 2018

Molecular regulation of neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

7 January 2021

based on heuristic

inferred from DOI database lookup

Defects in sensory axon growth precede neuronal death in Brn3a-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal death in the spinal ganglia of the chick embryo and its reduction by nerve growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

7 January 2021

based on heuristic

inferred from DOI database lookup

Cycloheximide phase-shifts, but does not prevent, de novo Krox-24 protein expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

7 January 2021

based on heuristic

inferred from DOI database lookup

Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

7 January 2021

based on heuristic

inferred from DOI database lookup

Brn-3a activates the expression of Bcl-x(L) and promotes neuronal survival in vivo as well as in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205842

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1205842

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/12203124

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