(Q50335820)

5 March 2018

title

Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells. (English)

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5 March 2018

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5 March 2018

author name string

Regnault A

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5 March 2018

Kleijmeer M

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5 March 2018

Ricciardi-Castagnoli P

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5 March 2018

Amigorena S

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publication date

1 October 1999

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5 March 2018

published in

Nature Cell Biology

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5 March 2018

volume

1

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5 March 2018

page(s)

362-368

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5 March 2018

issue

6

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5 March 2018

https://scigraph.springernature.com/pub.10.1038/14058

exact match

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cites work

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Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

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In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter.

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Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

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Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells.

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Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines

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Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells.

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Introduction of soluble protein into the class I pathway of antigen processing and presentation

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A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules

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Major histocompatibility complex class I presentation of peptides derived from soluble exogenous antigen by a subset of cells engaged in phagocytosis

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The efficiency of antigen delivery from macrophage phagosomes into cytoplasm for MHC class I-restricted antigen presentation

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Dendritic cells process exogenous viral proteins and virus-like particles for class I presentation to CD8+ cytotoxic T lymphocytes

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Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells

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LacZ inducible, antigen/MHC-specific T cell hybrids

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Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins

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Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells

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Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment

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Identifiers

DOI

10.1038/14058

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5 March 2018

PubMed ID

10559964

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5 March 2018