(Q50336184)

5 March 2018

title

Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation. (English)

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5 March 2018

CAAX-box protein maturation

main subject

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Gene Ontology release 2020-05-02

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3

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5 March 2018

Miguel C. Seabra

5

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5 March 2018

author name string

Ka Fai Leung

1

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5 March 2018

Rudi Baron

2

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5 March 2018

Anthony I Magee

4

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5 March 2018

language of work or name

English

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publication date

18 November 2006

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5 March 2018

Journal of Biological Chemistry

published in

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5 March 2018

volume

282

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5 March 2018

issue

2

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5 March 2018

page(s)

1487-1497

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5 March 2018

Thematic review series: lipid posttranslational modifications. Structural biology of protein farnesyltransferase and geranylgeranyltransferase type I

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Phosphoisoprenoids modulate association of Rab geranylgeranyltransferase with REP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Controlling the location and activation of Rab GTPases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M605557200

Thematic review series: lipid posttranslational modifications. CAAX modification and membrane targeting of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Isoprenylcysteine carboxyl methyltransferase deficiency in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Geranylgeranylated Rab proteins terminating in Cys-Ala-Cys, but not Cys-Cys, are carboxyl-methylated by bovine brain membranes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Carboxyl methylation of Ras regulates membrane targeting and effector engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Isoprenylation of Rab proteins possessing a C-terminal CaaX motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Membrane targeting of Rab GTPases is influenced by the prenylation motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Preparation of recombinant Rab geranylgeranyltransferase and Rab escort proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

A diffusion assay for detection and quantitation of methyl-esterified proteins on polyacrylamide gels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Nalpha -terminal acetylation of eukaryotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Post-translational processing of RhoA. Carboxyl methylation of the carboxyl-terminal prenylcysteine increases the half-life of Rhoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Nucleotide sequence of the yeast STE14 gene, which encodes farnesylcysteine carboxyl methyltransferase, and demonstration of its essential role in a-factor export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605557200

21 January 2018

Identifiers

DOI

10.1074/JBC.M605557200

1 reference

5 March 2018

PubMed ID

17114793

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5 March 2018