(Q50336648)

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Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation

scientific article published on 25 January 2007

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation (English)

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

phosphorylation

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Sumana Chandramouli

3

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

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Dieu-Hung Lao

1

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Permeen Yusoff

2

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Robin J Philp

4

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Chee Wai Fong

5

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Rebecca A Jackson

6

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Tzuen Yih Saw

7

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Chye Yun Yu

8

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Graeme R Guy

9

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

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publication date

25 January 2007

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

282

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

12

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

9117-9126

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Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Sprouty, an intracellular inhibitor of Ras signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of adapter proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Regulation of Raf-1 by direct feedback phosphorylation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Sprouty: how does the branch manager work?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Regulation of sprouty stability by Mnk1-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607563200

21 January 2018

Identifiers

10.1074/JBC.M607563200

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/17255109

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