(Q50455260)

14 March 2018

title

BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2. (English)

1 reference

14 March 2018

author

Sonia Barroso

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

María L García-Rubio

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Andrés Aguilera

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Vaibhav Bhatia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Emanuela Tumini

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Emilia Herrera-Moyano

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Emilia Herrera-Moyano

5

1 reference

14 March 2018

language of work or name

English

0 references

publication date

1 June 2014

1 reference

14 March 2018

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

7509

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

362-365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24896180%20AND%20SRC:MED&resulttype=core&format=json

R loops: from transcription byproducts to threats to genome stability

6 June 2020

cites work

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Human capping enzyme promotes formation of transcriptional R loops in vitro

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R-loop-mediated genomic instability is caused by impairment of replication fork progression

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Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes

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R-loops cause replication impairment and genome instability during meiosis

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Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles

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Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export

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SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope

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The human TREX-2 complex is stably associated with the nuclear pore basket.

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Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism

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Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex

21 January 2018

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DSS1 is required for the stability of BRCA2

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Direct observation of individual endogenous protein complexes in situ by proximity ligation

21 January 2018

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Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

21 January 2018

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R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters

21 January 2018

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Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication

21 January 2018

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Reduced FANCD2 influences spontaneous SCE and RAD51 foci formation in uveal melanoma and Fanconi anaemia

21 January 2018

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The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores.

21 January 2018

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Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

21 January 2018

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

21 January 2018

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A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

21 January 2018

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How the fanconi anemia pathway guards the genome

21 January 2018

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BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

21 January 2018

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The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides

21 January 2018

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ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes

21 January 2018

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Impairment of transcription elongation by R-loops in vitro

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24896180

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sister chromatid exchange

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13374