(Q50501228)

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IMB2026791, a xanthone, stimulates cholesterol efflux by increasing the binding of apolipoprotein A-I to ATP-binding cassette transporter A1.

scientific article published on 7 March 2012

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399138%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

IMB2026791, a xanthone, stimulates cholesterol efflux by increasing the binding of apolipoprotein A-I to ATP-binding cassette transporter A1 (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399138%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Jikai Liu

1

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25 January 2020

Zhongbing Zhang

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399138%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Yanni Xu

3

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25 January 2020

Tingting Feng

4

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25 January 2020

Wei Jiang

5

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25 January 2020

Zhuorong Li

6

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25 January 2020

Bin Hong

7

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25 January 2020

Zijian Xie

8

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25 January 2020

Shuyi Si

9

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25 January 2020

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7 March 2012

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25 January 2020

1 reference

Europe PubMed Central

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25 January 2020

17

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25 January 2020

3

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25 January 2020

2833-2854

1 reference

Europe PubMed Central

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25 January 2020

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Creative Commons Attribution 4.0 International

7 March 2012

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April 2022 Public Data File from Crossref

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0 references

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel mutations in the gene encoding ATP-binding cassette 1 in four tangier disease kindreds

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP binding cassette transporter ABCA1 modulates the secretion of apolipoprotein E from human monocyte-derived macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of apolipoprotein A-I helix 10 in apolipoprotein-mediated cholesterol efflux via the ATP-binding cassette transporter ABCA1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular phospholipid and cholesterol efflux in high-density lipoprotein deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into the role of the adenosine triphosphate-binding cassette transporters in high-density lipoprotein metabolism and reverse cholesterol transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation and Mechanisms of ATP-Binding Cassette Transporter A1-Mediated Cellular Cholesterol Efflux

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-inhibition of SR-BI- and ABCA1-mediated cholesterol transport by the small molecules BLT-4 and glyburide

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulatory networks in lipid metabolism control ABCA1 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of upregulators of human ATP-binding cassette transporter A1 via high-throughput screening of a synthetic and natural compound library

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jadomycin B, an Aurora-B kinase inhibitor discovered through virtual screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulations of the key mediators in inflammation and atherosclerosis by aspirin in human macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/22399138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES17032833

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399138%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399138%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22399138%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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