(Q50512911)

English

Toxicity of non-abeta component of Alzheimer's disease amyloid, and N-terminal fragments thereof, correlates to formation of beta-sheet structure and fibrils.

scientific article published in April 2000

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

Toxicity of non-abeta component of Alzheimer's disease amyloid, and N-terminal fragments thereof, correlates to formation of beta-sheet structure and fibrils. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

Alzheimer's disease

1 reference

based on heuristic

inferred from title

author name string

A M Bodles

1

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

D J Guthrie

2

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

P Harriott

3

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

P Campbell

4

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

G B Irvine

5

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

language of work or name

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publication date

1 April 2000

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

267

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

8

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

2186-2194

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

The N-terminal region of non-A beta component of Alzheimer's disease amyloid is responsible for its tendency to assume beta-sheet and aggregate to form fibrils

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Non-A beta component of Alzheimer's disease amyloid (NAC) is amyloidogenic

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Isoform-specific binding of human apolipoprotein E to the non-amyloid beta component of Alzheimer's disease amyloid.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

The awakening of α-synuclein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: is NAC a common trigger or target in neurodegenerative disease?

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

The intracellular component of cellular 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction is specifically inhibited by beta-amyloid peptides.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Conformations of synthetic beta peptides in solid state and in aqueous solution: relation to toxicity in PC12 cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.2000.01219.X

21 January 2018

Identifiers

10.1046/J.1432-1327.2000.01219.X

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

release_2gim4s77mjhwfmt2vdzajpzmn4

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https://api.fatcat.wiki/v0/release/2gim4s77mjhwfmt2vdzajpzmn4

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 March 2018

http://europepmc.org/abstract/MED/10759841

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