(Q50513019)

14 March 2018

title

LacI mutation spectra following benzo[a]pyrene treatment of Big Blue mice. (English)

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14 March 2018

author name string

Shane BS

1

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14 March 2018

de Boer J

2

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14 March 2018

Watson DE

3

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14 March 2018

Haseman JK

4

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14 March 2018

Glickman BW

5

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14 March 2018

Tindall KR

6

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14 March 2018

language of work or name

English

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publication date

1 April 2000

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14 March 2018

published in

Carcinogenesis

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14 March 2018

volume

21

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14 March 2018

issue

4

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14 March 2018

page(s)

715-725

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14 March 2018

Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite

cites work

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

A transversion mutation hypothesis for chemical carcinogenesis by N2-substitution of guanine in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

The Major, N2-Gua Adduct of the (+)-anti-Benzo[a]pyrene Diol Epoxide Is Capable of Inducing G.fwdarw.A and G.fwdarw.C, in Addition to G.fwdarw.T, Mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

How are potent bulky carcinogens able to induce such a diverse array of mutations?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Radical cations in aromatic hydrocarbon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutational spectra vary with exposure conditions: benzo[a]pyrene in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Requirement of mammalian DNA polymerase-beta in base-excision repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Infidelity of DNA synthesis associated with bypass of apurinic sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutagenicity of a unique apurinic/apyrimidinic site in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutation-spectrum of a true abasic site in codon 12 of a c-Ha-ras gene in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutagenesis by apurinic sites in normal and ataxia telangiectasia human lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Coding properties of a unique apurinic/apyrimidinic site replicated in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutant frequency of lacI in transgenic mice following benzo[a]pyrene treatment and partial hepatectomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

A comparative study of in vivo mutation assays: analysis of hprt, lacI, cII/cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

The mutagenicity of benzo[a]pyrene in mouse small intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Comparative dose-response tumorigenicity studies of dibenzo[alpha,l]pyrene versus 7,12-dimethylbenz[alpha]anthracene, benzo[alpha]pyrene and two dibenzo[alpha,l]pyrene dihydrodiols in mouse skin and rat mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Sequence of the lacI gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Frameshift mutations and the genetic code. This paper is dedicated to Professor Theodosius Dobzhansky on the occasion of his 66th birthday

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutation spectra in Salmonella of complex mixtures: comparison of urban air to benzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Induction of specific frameshift and base substitution events by benzo[a]pyrene diol epoxide in excision-repair-deficient Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Kinds of mutations formed when a shuttle vector containing adducts of benzo[a]pyrene-7,8-diol-9,10-epoxide replicates in COS7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

DNA base changes in benzo [α]pyrene diol epoxide-induced dihydrofolate reductase mutants of Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutational spectra in the lacl gene in skin from 7,12-dimethylbenz[a]anthracene-treated and untreated transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Excision repair at individual bases of the Escherichia coli lacI gene: relation to mutation hot spots and transcription coupling activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Genetic studies of the lac repressor. VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Statistical design and analysis of mutation studies in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Sources of variability in data from a lacI transgenic mouse mutation assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Spontaneous mutation in lacI transgenic mice: a comparison of tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutational consequences of replication of M13mp7L2 constructs containing cis-opened benzo[a]pyrene 7,8-diol 9, 10-epoxide-deoxyadenosine adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Spontaneous and ENU-induced mutation spectra at the cII locus in Big Blue Rat2 embryonic fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-ni

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Flanking base effects on the structural conformation of the (+)-trans-anti-benzo[a]pyrene diolepoxide adduct to N2-dG in sequence-defined oligonucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Sequence specificity of mutations induced by benzo[a]pyrene-7,8-diol-9,10-epoxide at endogenous aprt gene in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Kinds of mutations formed when a shuttle vector containing adducts of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene replicates in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Base insertion and deletion mutations induced in an Escherichia coli plasmid by benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutation spectrum of cigarette smoke condensate in Salmonella: comparison to mutations in smoking-associated tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Origins of stereospecificity in DNA damage by anti-benzo[a]pyrene diol-epoxides. A molecular modelling study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Molecular mechanics simulations on covalent complexes between polycyclic carcinogens and B-DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

The role of adduct site-specific mutagenesis in understanding how carcinogen-DNA adducts cause mutations: perspective, prospects and problems

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: what controls mutagenic specificity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

A comparison of mutational specificity of mutations induced by S9-activated B[a]P and benzo[a]pyrene-7,8-diol-9,10-epoxide at the endogenous aprt gene in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Formation and persistence of benzo(a)pyrene metabolite-DNA adducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

The 'A rule' of mutagen specificity: a consequence of DNA polymerase bypass of non-instructional lesions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Relating aromatic hydrocarbon-induced DNA adducts and c-H-ras mutations in mouse skin papillomas: the role of apurinic sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Mutagenic properties of a unique abasic site in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Determination of benzo[a]pyrene- and 7,12-dimethylbenz[a]anthracene-DNA adducts formed in rat mammary glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Depurinating and stable benzo[a]pyrene-DNA adducts formed in isolated rat liver nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Depurination-induced infidelity of deoxyribonucleic acid synthesis with purified deoxyribonucleic acid replication proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Inhibition of benzo[a]pyrene-induced mutagenesis by (-)-epigallocatechin gallate in the lung of rpsL transgenic mice

21 January 2018

1 reference

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Mechanisms of ultraviolet-induced mutation. Mutational spectra in the Escherichia coli lacI gene for a wild-type and an excision-repair-deficient strain

21 January 2018

1 reference

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Primer Extension by Various Polymerases Using Oligonucleotide Templates Containing Stereoisomeric Benzo[a]pyrene-Deoxyadenosine Adducts

21 January 2018

1 reference

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Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2F21.4.715

Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene)

21 January 2018

1 reference

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Sequence preferences of covalent DNA binding by anti-(+)- and anti-(-)-benzo[a]pyrene diol epoxides

21 January 2018

1 reference

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Synthesis of adducts formed by iodine oxidation of aromatic hydrocarbons in the presence of deoxyribonucleosides and nucleobases

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/CARCIN/21.4.715

1 reference

14 March 2018

1 reference

14 March 2018