(Q50513227)

14 March 2018

title

Differential cytotoxicity and induction of apoptosis in tumor and normal cells by hydroxymethylacylfulvene (HMAF). (English)

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14 March 2018

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Woynarowska BA

1

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14 March 2018

Woynarowski JM

2

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14 March 2018

Herzig MC

3

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14 March 2018

Roberts K

4

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14 March 2018

Higdon AL

5

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14 March 2018

MacDonald JR

6

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14 March 2018

language of work or name

English

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publication date

1 May 2000

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14 March 2018

published in

Biochemical Pharmacology

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14 March 2018

volume

59

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14 March 2018

issue

10

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14 March 2018

page(s)

1217-1226

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14 March 2018

Preclinical evaluation of illudins as anticancer agents: basis for selective cytotoxicity

cites work

1 reference

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Efficacy of HMAF (MGI-114) in the MV522 metastatic lung carcinoma xenograft model nonresponsive to traditional anticancer agents

7 January 2021

1 reference

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Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114)

7 January 2021

1 reference

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Drug uptake and cellular targets of hydroxymethylacylfulvene (HMAF)

7 January 2021

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DNA adducts from chemotherapeutic agents

7 January 2021

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Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells

7 January 2021

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NCM460, a normal human colon mucosal epithelial cell line

7 January 2021

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Pilocarpine, a salivary gland radioprotectant, does not inhibit cytotoxic effect of gamma-radiation on squamous cell carcinoma in vitro

7 January 2021

1 reference

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New colorimetric cytotoxicity assay for anticancer-drug screening

7 January 2021

1 reference

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Single-step procedure for labeling DNA strand breaks with fluorescein- or BODIPY-conjugated deoxynucleotides: detection of apoptosis and bromodeoxyuridine incorporation.

7 January 2021

1 reference

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Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53

7 January 2021

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p53-induced apoptosis in the human T-ALL cell line CCRF-CEM.

7 January 2021

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bcl-2 over-expression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells

7 January 2021

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Increasing the susceptibility of the rat 208F fibroblast cell line to radiation-induced apoptosis does not alter its clonogenic survival dose-response

7 January 2021

1 reference

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Cellular heterogeneity in DNA damage and growth inhibition induced by ICI D1694, thymidylate synthase inhibitor, using single cell assays

7 January 2021

1 reference

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Growth slow-down and growth arrest of human colon carcinoma cells HCT-8 in vitro after exposure to 5-fluoro-2'-deoxyuridine

7 January 2021

1 reference

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The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

7 January 2021

1 reference

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Apoptosis- and necrosis-inducing potential of cladribine, cytarabine, cisplatin, and 5-fluorouracil in vitro: a quantitative pharmacodynamic model.

7 January 2021

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Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.

7 January 2021

1 reference

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Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

7 January 2021

1 reference

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The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition

7 January 2021

1 reference

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Thiol-mediated redox regulation of neutrophil apoptosis

7 January 2021

1 reference

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Redox regulation of cellular signalling

7 January 2021

1 reference

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Thioredoxin redox control of cell growth and death and the effects of inhibitors

7 January 2021

1 reference

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Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

7 January 2021

1 reference

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Interaction of quinones with Arabidopsis thaliana thioredoxin reductase

7 January 2021

1 reference

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Prooxidant-antioxidant shift induced by androgen treatment of human prostate carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900254-9

Bcl-2 alters the balance between apoptosis and necrosis, but does not prevent cell death induced by oxidized low density lipoproteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2800%2900254-9

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(00)00254-9

1 reference

14 March 2018

release_o35w5wouirelfc46hanzttfdwe

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/o35w5wouirelfc46hanzttfdwe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

14 March 2018