(Q50526646)

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Counter-modulation of fatty acid-induced pro-inflammatory nuclear factor κB signalling in rat skeletal muscle cells by AMP-activated protein kinase.

scientific article published in April 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21323644%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Counter-modulation of fatty acid-induced pro-inflammatory nuclear factor κB signalling in rat skeletal muscle cells by AMP-activated protein kinase (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21323644%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

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skeletal muscle cell

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Charlotte J Green

1

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Europe PubMed Central

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22 January 2020

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22 January 2020

Harinder S Hundal

6

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22 January 2020

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Katherine Macrae

2

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22 January 2020

Sarah Fogarty

3

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22 January 2020

Kei Sakamoto

5

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22 January 2020

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1 April 2011

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22 January 2020

Biochemical Journal

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22 January 2020

435

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22 January 2020

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22 January 2020

463-474

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22 January 2020

The role of interleukins in insulin resistance and type 2 diabetes mellitus.

1 reference

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Saturated fatty acids and insulin resistance

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Palmitate-induced interleukin 6 production is mediated by protein kinase C and nuclear-factor kappaB activation and leads to glucose transporter 4 down-regulation in skeletal muscle cells.

1 reference

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Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor-kappaB.

1 reference

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Fatty acid-induced inflammation and insulin resistance in skeletal muscle and liver

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Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

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Lipid induced overexpression of NF-kappaB in skeletal muscle cells is linked to insulin resistance.

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TLR4 links innate immunity and fatty acid-induced insulin resistance

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Integrating cell-signalling pathways with NF-kappaB and IKK function

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IKK-beta links inflammation to obesity-induced insulin resistance

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Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

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p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

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The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

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21 January 2018

Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner

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PKC- and ERK-dependent activation of I kappa B kinase by lipopolysaccharide in macrophages: enhancement by P2Y receptor-mediated CaMK activation

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Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation

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Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

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21 January 2018

5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.

1 reference

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21 January 2018

5-aminoimidazole-4-carboxamide ribonucleoside and AMP-activated protein kinase inhibit signalling through NF-κB.

1 reference

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21 January 2018

5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.

1 reference

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21 January 2018

The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells

1 reference

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21 January 2018

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

1 reference

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21 January 2018

Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding

1 reference

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21 January 2018

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

1 reference

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21 January 2018

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase

1 reference

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21 January 2018

A new mathematical model for relative quantification in real-time RT-PCR

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21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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21 January 2018

Regulation of glucose transport and glycogen synthesis in L6 muscle cells during oxidative stress. Evidence for cross-talk between the insulin and SAPK2/p38 mitogen-activated protein kinase signaling pathways

1 reference

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21 January 2018

The selectivity of protein kinase inhibitors: a further update

1 reference

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21 January 2018

Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes

1 reference

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21 January 2018

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells.

1 reference

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21 January 2018

Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

1 reference

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21 January 2018

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

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21 January 2018

Obesity, inflammation, and insulin resistance--a mini-review

1 reference

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21 January 2018

Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

1 reference

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21 January 2018

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

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21 January 2018

Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells

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21 January 2018

Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells

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Phorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways

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Multiple Toll-like receptor ligands induce an IL-6 transcriptional response in skeletal myocytes

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Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

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AMPK: a key sensor of fuel and energy status in skeletal muscle

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AMPK: an emerging drug target for diabetes and the metabolic syndrome

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Metformin inhibits TNF-alpha-induced IkappaB kinase phosphorylation, IkappaB-alpha degradation and IL-6 production in endothelial cells through PI3K-dependent AMPK phosphorylation

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Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment

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Identification of Raf-1 Ser621 kinase activity from NIH 3T3 cells as AMP-activated protein kinase

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Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

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Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes.

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21 January 2018

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